Mixed adenoneuroendocrine carcinoma: case report




Ángel A. Hernández-Moreno, Servicio de Cirugía Plástica y Reconstructiva, Hospital Regional Lic. Adolfo López Mateos, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Ciudad de México, México
Carlos E. Durón-Gutiérrez, Servicio de Cirugía General, Hospital General Tacuba, ISSSTE, Ciudad de México, México
Sheyla P. Serrano-González, Servicio de Cirugía General, Hospital General Tacuba, ISSSTE, Ciudad de México, México
Grettel León-Martínez, Servicio de Anatomía Patológica, Hospital General Tacuba, ISSSTE, Ciudad de México, México
José G. Arroyo-Del-Castillo, Servicio de Neurocirugía, Instituto Nacional de Neurología y Neurocirugía, Secretaría de Salud de la Ciudad de México. Ciudad de México, México


Introducción: Mixed adenoneuroendocrine carcinoma is a rare tumor of the gastrointestinal tract with double differentiation into adenomatous and neuroendocrine carcinoma, each component with at least 30%. Case report: A 60-year-old female with acute abdominal pain. Surgical treatment was decided, finding a tumor at the level of the cecum and ascending colon, a right hemicolectomy and ileostomy were performed. Discussion: Mixed adenoneuroendocrine carcinoma can appear in various organs. They are highly malignant tumors, with a high risk of metastasis. Conclusions: These tumors do not present symptoms or specific radiological or laboratory findings; diagnosis depends on postoperative histopathological and immunohistochemical studies.



Keywords: Mixed adenoneuroendocrine carcinoma. Adenocarcinomatous differentiation. Neuroendocrine differentiation. Colorectal cancer.