Role of contrast agent in evaluation of periprostatic invasion in prostate cancer




Hüseyin A. Kızıloğlu, Department of Radiology, Tokat Gaziosmanpaşa University Faculty of Medicine, Tokat, Türkiye
Murat Beyhan, Department of Radiology, Tokat Gaziosmanpaşa University Faculty of Medicine, Tokat, Türkiye
Erkan Gökçe, Department of Radiology, Tokat Gaziosmanpaşa University Faculty of Medicine, Tokat, Türkiye
Yaşar Birişik, Department of Radiology, Tokat Gaziosmanpaşa University Faculty of Medicine, Tokat, Türkiye
Çiğdem Samur Salbaş, Department of Radiology, Bandırma Training and Research Hospital, Balıkesir, Türkiye
Mustafa Yeşilyurt, Department of Radiology, Erzurum Training and Research Hospital, Erzurum. Türkiye


Objectives: Our study aims to demonstrate the detection of invasion by biparametric prostate MRI (bpMRI). Materials and methods: The cases whose histopathological diagnosis was prostate cancer (PCa) and whose mpMRI report was reported as PIRADS 4 and 5 were evaluated retrospectively by two radiologists with different prostate imaging experiences. The images were grouped into two data sets. Dataset-1 was bpMRI, and dataset-2 was mpMRI. Two radiologists first evaluated dataset-1 independently of each other, and 1 month later, dataset-2. They recorded whether there was an invasion and where it was seen in the patients. Then, the results were compared. Results: A total of 75 patients were included in the study. Periprostatic invasion was detected in 33 of the patients. Both the 1st reader and the 2nd reader image detected all the cases with invasion (100%) separately between dataset-1 and set-2. Compatibility for image dataset-1 and dataset-2 between both readers was observed to be excellent. Conclusions: There is no need to use contrast agent to evaluate periprostatic invasion and to have an idea about local staging in PCa patients.



Keywords: Periprostatic invasion. Contrast agent. Prostate. Multiparametric. Biparametric.