Comparison of quality of life after radical treatment in prostate cancer: radical prostatectomy versus external radiotherapy




Laura Vera-Álamo, Servicio de Urología, Complejo Hospitalario Universitario Insular-Materno Infantil de Gran Canaria, Las Palmas, España
Paula Léon-Medina, Servicio de Urología, Complejo Hospitalario Universitario Insular-Materno Infantil de Gran Canaria; Departamento de Urología, Universidad de Las Palmas de Gran Canaria; Las Palmas, España
Carmen N. Hernández-Flores, Departamento de Matemáticas, Universidad de Las Palmas de Gran Canaria. Las Palmas, España
José V. Armas-Molina, Servicio de Urología, Complejo Hospitalario Universitario Insular-Materno Infantil de Gran Canaria; Departamento de Urología, Universidad de Las Palmas de Gran Canaria; Las Palmas, España
José L. Artiles-Hernández, Servicio de Urología, Complejo Hospitalario Universitario Insular-Materno Infantil de Gran Canaria, Las Palmas, España


Objective: To assess and compare the functional and quality of life results in patients treated with curative intent for localized prostate cancer during 2015 in our hospital. Method: 77 patients treated by radical prostatectomy or external radiotherapy with androgen deprivation were prospective enrolled. Expanded Prostate Cancer Index Composite for Clinical Practice (EPIC-CP) questionnaire at 3-year follow-up and Spanish Questionnaire on Quality of Life in Patients with Prostate Cancer (CAVIPRES-30) at diagnosis and at 3-year follow-up were registered. Results: 68 patients were included, 39 patients treated by radical prostatectomy and 29 received external radiotherapy with androgen deprivation. Among the operated patients, 61.5% were dry and 17.9% use three or more daily pads, compared to 72.4% and 6.8%, respectively, in the radiotherapy group. 48.7% of prostatectomized patients reported very poor or no capacity to have a sufficiently rigid erection, compared to 69% of the radiated group. After surgery, 43.6% considered bad or very bad quality-of-life, compared to 68.9% in the radiotherapy group. In the comparison of the data of the pre- and post-treatment questionnaire can be seen that the patients had a superior perception before the procedure. Conclusions: Patients treated by surgery have a better perception of quality-of-life compared to those treated by radiotherapy.



Keywords: Prostate cancer. Radical prostatectomy. External radiotherapy. Quality of life. Questionnaire.