Sarish Del Real-Ordoñez, Departamento de Ginecología Oncológica, Centro Oncológico Región Sureste, Saltillo, Coahuila, México
Nancy Reynoso-Noveron, Dirección de Investigación, Instituto Nacional de Cancerología, Ciudad de México, México
María D. Pérez-Montiel, Departamento de Patología, Instituto Nacional de Cancerología, Ciudad de México, México
Rosa A. Salcedo-Hernández, Departamento de Ginecología Oncológica, Instituto Nacional de Cancerología, Ciudad de México, México
Salim A. Barquet-Muñoz, Departamento de Ginecología Oncológica, Instituto Nacional de Cancerología, Ciudad de México, México
David Isla-Ortiz, Departamento de Ginecología Oncológica, Instituto Nacional de Cancerología, Ciudad de México, México
Objective: To determine the validity of sentinel lymph node biopsy (SNB) in women with early-stage cervical cancer (CeCa). Methods: We carried out a study of 46 patients with CeCa of FIGO stages IA1c-IB2 treated with radical uterine surgery. The technique for the identification of BGC was performed with patent blue dye and technetium-99m. For its validation, a bilateral pelvic lymphadenectomy (BPL) was performed, and all sentinel lymph nodes underwent pathological ultra-staging. We determined the detection rates of SNB, bilaterality, sensitivity, specificity, and negative and positive predictive values. Results: The sensitivity of the SNB was 100%, specificity was 95%, positive predictive value was 75%, negative predictive value was 100%, diagnostic accuracy was 93%, and the false negative rate was 0%. Conclusions: The BGC technique in patients with CeCa in the early stages who undergo radical hysterectomy is a feasible and safe method at Instituto Nacional de Cancerología. The importance of this method is that BPL can be avoided when it migrates bilaterally, reducing the morbidity of the procedure.
Keywords: Sentinel lymph node. Cervix cancer. Lymphadenectomy.